[Home ] [Archive]    
:: Main :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 1, Issue 2 (Oct-Dec 2014) ::
Nutr Food Sci Res 2014, 1(2): 27-33 Back to browse issues page
Association of Macro- and Micro-nutrients Intake with the Risk of Multiple Sclerosis: A Case Control Study
Maryam Behrooz, Golaleh Asghari, Zohreh Hosseini, Parvin Mirmiran, Bahram Rashidkhani *
Community Nutrition Department, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute (WHO Collaborating Center), Shahid Beheshti University of Medical Sciences, Tehran, Iran , rashidkhani@yahoo.com
Abstract:   (5926 Views)
Background and Objectives: Multiple Sclerosis (MS) is the most prevalent autoimmune disease of the central nervous system, and it has been suggested that nutrition might play a role in the etiology of MS. This study was aimed to evaluate the relationship between MS risk and intake of some macro- and micro-nutrients in Tehran (Iran). Materials and Methods: In this hospital based, case-control study, a total of 60 newly diagnosed patients with MS and 140 controls underwent face-to-face interviews. Information regarding the usual dietary intake of each individual in the past year was collected by using a valid and reliable 168-item semi-quantitative food frequency questionnaire. Multivariate logistic regression was used to estimate the odds ratios and 95% confidence intervals. Results: Inverse significant associations were observed (P< 0.05) between the intake of protein (OR=0.19 95% CI: 0.04-0.76) and micro-nutrients such as vitamin B1 (OR=0.10 95% CI: 0.02-0.53) , vitamin B2 (OR=0.15 95% CI: 0.04-0.50), cobalamin (OR=0.13 95% CI: 0.04-0.38), vitamin C (OR=0.20 95% CI: 0.07-0.58), vitamin A (OR=0.23 95% CI: 0.09-0.59), vitamin D (OR=0.28 95% CI: 0.11-0.72), vitamin E (OR=0.15 95% CI: 0.05-0.41), β-carotene (OR=0.38 95% CI: 0.15-0.97), zinc (OR=0.05 95% CI: 0.01-0.27), magnesium (OR=0.12 95% CI: 0.03-0.47) and calcium (OR=0.23 95% CI: 0.08-0.67) and the risk of MS. Conclusions: The results suggest that intake of some macro- and micro-nutrients might be associated with reduced risk of MS. It seems promising that intake of nutrients at least in the dietary reference levels may decrease the risk of MS. Keywords: Multiple Sclerosis (MS) Micronutrients Case-control study
Keywords: Multiple Sclerosis (MS), Micronutrients, Case-control study
Full-Text [PDF 115 kb]   (3303 Downloads)    
Article type: Research | Subject: Food Science
Received: 2014/12/10 | Accepted: 2015/01/26 | Published: 2015/01/26
Send email to the article author

Add your comments about this article
Your username or Email:


XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Behrooz M, Asghari G, Hosseini Z, Mirmiran P, Rashidkhani B. Association of Macro- and Micro-nutrients Intake with the Risk of Multiple Sclerosis: A Case Control Study. Nutr Food Sci Res. 2014; 1 (2) :27-33
URL: http://nfsr.sbmu.ac.ir/article-1-66-en.html

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 1, Issue 2 (Oct-Dec 2014) Back to browse issues page
Nutrition and Food Sciences Research
Persian site map - English site map - Created in 0.05 seconds with 30 queries by YEKTAWEB 4419