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:: Volume 1, Issue 2 (Oct-Dec 2014) ::
Nutr Food Sci Res 2014, 1(2): 27-33 Back to browse issues page
Association of Macro- and Micro-nutrients Intake with the Risk of Multiple Sclerosis: A Case Control Study
Maryam Behrooz , Golaleh Asghari , Zohreh Hosseini , Parvin Mirmiran , Bahram Rashidkhani
MD, PhD Community Nutrition Department, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute (WHO Collaborating Center), Shahid Beheshti University of Medical Sciences, Tehran, Iran
Abstract:   (2928 Views)
Background and Objectives: Multiple Sclerosis (MS) is the most prevalent autoimmune disease of the central nervous system, and it has been suggested that nutrition might play a role in the etiology of MS. This study was aimed to evaluate the relationship between MS risk and intake of some macro- and micro-nutrients in Tehran (Iran). Materials and Methods: In this hospital based, case-control study, a total of 60 newly diagnosed patients with MS and 140 controls underwent face-to-face interviews. Information regarding the usual dietary intake of each individual in the past year was collected by using a valid and reliable 168-item semi-quantitative food frequency questionnaire. Multivariate logistic regression was used to estimate the odds ratios and 95% confidence intervals. Results: Inverse significant associations were observed (P< 0.05) between the intake of protein (OR=0.19 95% CI: 0.04-0.76) and micro-nutrients such as vitamin B1 (OR=0.10 95% CI: 0.02-0.53) , vitamin B2 (OR=0.15 95% CI: 0.04-0.50), cobalamin (OR=0.13 95% CI: 0.04-0.38), vitamin C (OR=0.20 95% CI: 0.07-0.58), vitamin A (OR=0.23 95% CI: 0.09-0.59), vitamin D (OR=0.28 95% CI: 0.11-0.72), vitamin E (OR=0.15 95% CI: 0.05-0.41), β-carotene (OR=0.38 95% CI: 0.15-0.97), zinc (OR=0.05 95% CI: 0.01-0.27), magnesium (OR=0.12 95% CI: 0.03-0.47) and calcium (OR=0.23 95% CI: 0.08-0.67) and the risk of MS. Conclusions: The results suggest that intake of some macro- and micro-nutrients might be associated with reduced risk of MS. It seems promising that intake of nutrients at least in the dietary reference levels may decrease the risk of MS. Keywords: Multiple Sclerosis (MS) Micronutrients Case-control study
Keywords: Multiple Sclerosis (MS), Micronutrients, Case-control study
Full-Text [PDF 115 kb]   (1579 Downloads)    
Type of Study: Research | Subject: General
Received: 2014/12/10 | Accepted: 2015/01/26 | Published: 2015/01/26
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Behrooz M, Asghari G, Hosseini Z, Mirmiran P, Rashidkhani B. Association of Macro- and Micro-nutrients Intake with the Risk of Multiple Sclerosis: A Case Control Study. Nutr Food Sci Res. 2014; 1 (2) :27-33
URL: http://nfsr.sbmu.ac.ir/article-1-66-en.html
Volume 1, Issue 2 (Oct-Dec 2014) Back to browse issues page
Nutrition and Food Sciences Research
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