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:: Volume 12, Issue 1 (Jan-Mar 2025) ::
Nutr Food Sci Res 2025, 12(1): 45-53 Back to browse issues page
Investigating Relationships of the Inflammatory Degrees of Malnutrition and Protein Quality with Risk Factors of Cardiovascular Diseases in Hemodialysis Patients
Mahsa Baghbani , Golnaz Majdizadeh , Zahra Mirali , Shahrzad Ossareh , Ariyo Movahedi *
Department of Nutrition, Science and Research Branch Islamic Azad University , amm35@mail.aub.edu
Abstract:   (739 Views)
Background and Objectives: Cardiovascular diseases are the most important causes of death in patients with chronic kidney failure, including hemodialysis patients. Inflammation is one of the major causes of increased malnutrition. An increase in the concentration of vascular inflammation factors in the blood such as the concentration of serum C-reactive protein is a strong predictor of mortality in hemodialysis patients. In this study, the relationship between the inflammatory degree of malnutrition and protein quality with risk factors of cardiovascular diseases in hemodialysis patients was assessed.
Materials and Methods: This descriptive-analytical cross-sectional study was carried out on 120 hemodialysis patients aged 20–80 y (57.43 ±15.58) in Tehran, Iran, using simple random sampling. General characteristics and anthropometric indices were recorded. Malnutrition-inflammation was assessed using questionnaires and food intake was investigated using  24-h recalls.
Results: Demographic and anthropometric characteristics were not significantly different between groups with heart diseases (P<0.05). No significant correlation was observed between the indicators of malnutrition-inflammation and suffering from heart diseases in hemodialysis patients (P<0.05). No significant relationship was reported between the quality index of dietary proteins and heart diseases (P<0.05).
Conclusions: No significant relationship was detected between the inflammatory degrees of malnutrition and protein quality and the risk factors of cardiovascular diseases in hemodialysis patients. Further studies are highly suggested.
Keywords: Malnutrition, Cardiovascular disease, Hemodialysis
Full-Text [PDF 573 kb]   (227 Downloads)    
Article type: Research | Subject: Nutrition
Received: 2024/09/7 | Accepted: 2024/11/16 | Published: 2025/02/9
  • To our knowledge, this research uniquely explores the relationship between malnutrition-inflammation and cardiovascular risk, employing comprehensive questionnaires and dietary recall methods to assess inflammatory levels and nutrition quality.
  • The findings indicate no significant correlation between malnutrition-inflammation indicators, dietary protein quality, and the incidence of heart disease in the studied population, which challenges existing assumptions about these relationships.
  • This research provides novel insights specifically related to hemodialysis patients, a group that experiences unique nutritional challenges and cardiovascular risks, contributing to the limited existing literature on this subject.
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Baghbani M, Majdizadeh G, Mirali Z, Ossareh S, Movahedi A. Investigating Relationships of the Inflammatory Degrees of Malnutrition and Protein Quality with Risk Factors of Cardiovascular Diseases in Hemodialysis Patients. Nutr Food Sci Res 2025; 12 (1) :45-53
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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 12, Issue 1 (Jan-Mar 2025) Back to browse issues page
Nutrition and food in health and disease
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