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Background and Objectives: Polycystic ovary syndrome (PCOS) is the greatest current endocrine disease in generative women. Although other issues such as insulin resistance, hyperinsulinemia, adiposity and dietary pattern are implied to be connected to PCOS, but the most recent evidence are needed to improve management of PCOS. Proteins and amino acids (key dietary components) can also have impact on this condition and may have therapeutic effects for handling this disorder. However, there is little information available in this area. So, the purpose of this study was to assess the connection between amino acids and protein intake and PCOS.
Materials and Methods: Science, Iran. Amino acids and proteins intake was estimated using validated food frequency questionnaire. Other factors such as ovarian disease, inherited predisposition, physical activity, the age of menarche and medical history were assessed by the questionnaire. Data analysis was represented by adjusted logistic by SPSS software version 15.
Results: The marked association among PCOS and ovarian disease (P < 0.001), age (P < 0.001) and consuming drugs (P = 0.001) were seen.  There was inversely associated between body mass index (BMI) and PCOS, but it was not remarkable (P = 0.068). But, no statistically significant connection was seen between the use of LEU (Lucien), MET (methionine), CYS (cysteine), PHE (phenylalanine), VAL (valine), ASP (asparagines), GLU (glutamic acid), and PCOS. Although, there was significant relationship between glycine, prolin, and methionine with PCOS.
Conclusions: According to the results of this study, significant relationship was observed between glycine, prolin, and methionine and BCAA/AAA ratio with PCOS.
 

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Background and Objectives: Sour-cherry seed is one of the waste products of the sour-cherry jam and juice processing. Sour cherries include two valuable wastes, including sour-cherry kernels and seed shells. The two sections have been reviewed and assessed.
Materials and Methods: In this study, total phenolic compounds, DPPH radical scavenging activity, cellulose, hemicellulose, lignin, BET surface area and density of sour-cherry seed powder were assessed. Cytotoxicity of the methanolic extract of sour-cherry shell was investigated on breast cancer cell lines (MCF-7).
Results: Sour-cherry seed included high quantities of total phenols (27.02 mg GAE/g db). The high-performance liquid chromatography analysis of phenols identified chlorogenic acid 1887.50 (µg/mg), 3,4-dihydroxybenzoic acid 262.30 (µg/mg), quercetin 13.50 (µg/mg) and rutin 58.45 (µg/mg). Results reported 1.490, 36.65, 17.68 and 37.2% db of hemicellulose, cellulose and lignin content, respectively. Sour-cherry and walnut shell methanolic extracts significantly decreased MCF-7 cell growth (p <0.05) in a dose-dependent manner. The methanol extracts of walnut shells and sour-cherry seeds showed cytotoxic activities against MCF-7 cells with IC₅₀ values of 0.47 and 0.97 mg/mL respectively. Kernels included 17% oil and 28.4% protein. Sour-cherry kernel oil included palmitic acid (5.93), stearic acid (3.3), arachidic acid (1.26), oleic acid (45.03), linoleic acid (40.61) and linolenic acid (3.87). Quantity of total phenolic compounds was reported as 6.41 mg gallic acid per gram.
Conclusions: In conclusion, sour-cherry seed showed good physical characteristics, including potentials to be used in sports drinks, health supplements, pharmaceutical carriers and biosorbents. Preliminary data on characteristics of the sour-cherry seed can provide useful information for potential uses in natural supplements as well as healthy foods.