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Showing 2 results for Antioxidants
Uchechi Onyedikachi, Callistus Chukwuebuka, George Chigozie, Uroko Ikechukwu,
Volume 9, Issue 4 (12-2022)
Abstract
Background and Objectives: Nutrient composition of vegetables is critical for diet supplementation and disease management in phytomedicine. This study analyzed phytochemical and vitamin contents and antioxidant potentials of methanolic extracts of leaves and stems from Ocimum gratissimum (OG), Telfairia occidentalis (TO), Vernonia amygdalina (VA) and Gongronema latifolium (GL) in Abia State, Nigeria.
Materials and Methods: This study analyzed phytochemicals, antioxidants and vitamins using standard analytical methods. Moreover, 2,2-diphenyl-1-picrylhydrazyl and ferric reducing antioxidant power were assessed using photometric assays.
Results: Phytochemical analyses showed the highest concentrations in phenolic contents of the leaf extracts and flavonoid contents of the stem extracts of OG (6.16 ±0.02 mg/100 g and 5.40 ±0.01 mg/100 mg, respectively). The 2,2-diphenyl-1-picrylhydrazyl assay indicated that the leaf extracts of TO and OG were consistently higher for scavenging activities at 100, 200 and 400 µg/ml concentrations, respectively. In contrast, stem extracts of VA and GL were higher at similar concentrations. The ferric reducing antioxidant power results demonstrated the highest values in the leaves and stems of OG (1.55 ±0.02 and 0.77 ±0.24 µm/fe(II)/l, respectively). Vitamin A and C compositions (mg/100 g) in the stem extracts were higher than those in the leaves; whereas, their leaf extracts included higher compositions of vitamin E (mg/100 g).
Conclusions: This study suggests conscious incorporation of stems and leaves as vegetables in diets to boost diet and supplement biological antioxidant defenses against oxidative stress-induced diseases, developing SDGs two(2) and three(3) with focusing on malnutrition and promoting health and well-being of all ages.
Jamal Rahmani, Ali Nikparast, Mehrnaz Nikkhah, Cain Ct Clark, Matin Ghanavati,
Volume 10, Issue 2 (7-2023)
Abstract
Background and Objectives: Age-related cataract (ARC) is a multifactorial progressive disease that causes blindness globally. Dietary antioxidants such as vitamins and carotenoids have been reported to attenuate oxidative stress as the major cause of ARC. However, associations between adherence to healthy dietary patterns and ARC must be understood. Up to date, adherence to the Nordic diet style assessed by two indices, including the healthy Nordic food index and Baltic Sea dietary score, have been associated with chronic diseases. This study aimed to investigate associations between the healthy Nordic food index and Baltic Sea dietary score and the odds of ARC in a case-control study, in Iran.
Materials and Methods: This hospital-based case-control study was carried out on 98 patients with ARC and 198 healthy controls were selected based on the inclusion criteria. A valid 168-item food frequency questionnaire was used to assess dietary intake over the last year. To investigate associations between the healthy Nordic food index and Baltic Sea dietary score and the risk of ARC, logistic regression tests were used.
Results: Adherence to the Baltic Sea dietary score was associated with lower risks of ARC in crude and adjusted models. After adjustment for potential confounders, participants in the highest quartile of Baltic Sea dietary score (compared to the lowest) had 75% lower age-related cataract risks (OR = 0.25; 95% CI = 0.11–0.56). The current results support previous results on the protective effects of dietary patterns rich in antioxidants on ARC.
Conclusions: Adherence to the Nordic eating style, including fruits and vegetables, whole grains, low-fat milk, fish, and healthy fats, assessed by the Baltic Sea dietary score may decrease risks of age-related ARC.
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