en Nutrition Nutrition Review Review <p style="text-align:justify"><span style="font-size:10pt"><span style="line-height:115%"><span style="tab-stops:409.5pt"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:11.0pt"><span style="line-height:115%">Background and Objectives: </span></span></b><b><span style="background:white"><span style="color:black">:</span></span></b><span style="background:white"><span style="color:black"> Hashimoto&#39;s <a name="_Hlk193522219">thyroiditis</a> is an autoimmune disorder that potentially induces hypothyroidism through immune-mediated destruction of the thyroid gland. Nutrients may play a critical role in modulating functionality of the immune system. </span></span><span style="color:black">The aim of this review was to provide a comprehensive summary of the available data on beneficial nutrients and dietary interventions for the management of <span style="background:white">Hashimoto&#39;s thyroiditis</span>.</span><span style="font-size:11.0pt"><span style="line-height:115%"></span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:115%"><span style="tab-stops:409.5pt"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:11.0pt"><span style="line-height:115%">Materials and Methods: </span></span></b><span style="color:black">A comprehensive search was carried out on databases such as PubMed, Scopus, ISI Web of Science and Embase, published 1990&ndash;2025, to identify all relevant articles that addressed the topics of nutrients, dietary patterns and Hashimoto&#39;s thyroiditis.</span><span style="font-size:11.0pt"><span style="line-height:115%"></span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:115%"><span style="tab-stops:409.5pt"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:11.0pt"><span style="line-height:115%">Results:</span></span></b><span style="background:white"><span style="color:black"> Certain nutrients might have a critical role in regulating the immune system. Supplementation with appropriate nutrients could potentially improve adverse effects associated with HT and enhance the overall quality of life for the patients. However, certain limitations such as contradictory results and restriction of randomized controlled trials investigating effects of nutrients and dietary patterns in patients with <a name="_Hlk193523515">Hashimoto&#39;s thyroiditis</a> were reported.</span></span><b> </b><span style="font-size:11.0pt"><span style="line-height:115%"></span></span></span></span></span></span></span><br> <span style="font-size:10pt"><span style="line-height:115%"><span style="tab-stops:409.5pt"><span style="unicode-bidi:embed"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:11.0pt"><span style="line-height:115%">Conclusions: </span></span></b><span style="background:white"><span style="color:black">Nutrients may include beneficial effects in management of Hashimoto&#39;s thyroiditis. Further studies are necessary to validate these findings and establish recommendations for patients with Hashimoto&#39;s thyroiditis.</span></span><span style="font-size:11.0pt"><span style="line-height:115%"></span></span></span></span></span></span></span></p> Hypothyroidism, Hashimoto’s thyroiditis, Diets, Nutrition management 1 9 http://nfsr.sbmu.ac.ir/browse.php?a_code=A-10-1160-1&slc_lang=en&sid=1 Fatemeh Bourbour Bourbour785@yahoo.com 10031947532846006966 10031947532846006966 No Department of Clinical Nutrition and Dietetic, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran Samira Rastgoo Rastgoo444@yahoo.com 10031947532846006967 10031947532846006967 No Department of Cellular and Molecular Nutrition, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Science and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran Morteza Seyed Khamoshi Khamoshi744@yahoo.com 10031947532846006968 10031947532846006968 No Department of Nutrition, Science and Research Branch, Tehran university of medical science, Tehran, Iran. Golbon Sohrab sadafrashidi1398@gmail.com 10031947532846006969 10031947532846006969 Yes Department of Clinical Ntion and Dietetic, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, utriTehran, Iran Saeid Kalbasi Kalbasi785@yahoo.com 10031947532846006970 10031947532846006970 No Internal Medicine Ward, Endocrinology and Metabolism section, Shahid Beheshti University of Medical Sciences, Tehran, Iran.