en Nutrition Nutrition Review Review Due to the lack of definite therapy and prevention protocols for Covid-19, nutrition and exercise are considered preventative measures in dealing with the epidemic. Healthy diets, dietary supplements and exercises boost the immune system. These factors can be effective in improving functions of the immune system. The current study investigated immune-enhancing characteristics of exercises, dietary supplements (proteins, vitamins, minerals, oils, coenzyme Q10 (CoQ10), probiotics, ginseng, antioxidants and <em>Chlorella vulgaris</em>) and food additives (titanium dioxide, sodium nitrite, monosodium glutamate, tartrazine, sweeteners and emulsifiers). The current study investigated functions of dietary supplements and exercises in strengthening the immune system, as well as assessing roles of food additives in illness prevention, particularly Covid-19, when combined with a balanced nutrition strategy. Light exercises, healthy lifestyles and nutritional supplements have been shown to boost the immune system. Covid-19, Dietary Supplement, Exercise, Food additive, Immune System 1 14 http://nfsr.sbmu.ac.ir/browse.php?a_code=A-10-976-1&slc_lang=en&sid=1 Amirhossein Abedini amirhsyn.abedini@sbmu.ac.ir 10031947532846005540 10031947532846005540 No Student Research Committee, Department of Food Science and Technology, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Science and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Aida Mahdavi aida.mdi90@yahoo.com 10031947532846005541 10031947532846005541 No Department of Food Science and Technology, Takestan Branch, Islamic Azad University, Qazvin, Iran Adel Mirza Alizadeh a.alizadeh@sbmu.ac.ir 10031947532846005542 10031947532846005542 No Student Research Committee, Department of Food Science and Technology, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Science and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Ehsan Hejazi ehsanhejazi@gmail.com 10031947532846005543 10031947532846005543 No Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran Hedayat Hosseini hedayat@sbmu.ac.ir 10031947532846005544 10031947532846005544 Yes Department of Food Science and Technology, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Science and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.