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:: Volume 5, Issue 3 (Jul-Sep 2018) ::
Nutr Food Sci Res 2018, 5(3): 11-16 Back to browse issues page
Association between Dietary Intake of Phytochemicals and hs-CRP in Healthy Women from Tehran: a Holistic Approach Using Dietary Phytochemical Index
Sareh Edalati , Beitolah Alipour , Bahram Rashidkhani
Department of community nutrition, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, Iran , saraedalati@yahoo.com
Abstract:   (7719 Views)
Background and Objectives: Although the anti-inflammatory effects of phytochemicals have been supported by several in vitro studies, their biological actions from regular diets are mixed. This study aimed to use dietary phytochemical index (DPI), as a food-based framework to assess dietary phytochemical intake and to understand its association with hs-CRP in a sample of Iranian women. Evaluation of the relationship between hs-CRP and several anthropometric indexes were also assessed.
Materials and Methods: A total of 170 visibly healthy premenopausal women with the mean age of 35.2 were selected from health centers of Tehran via multistage cluster random sampling. The usual dietary intakes were assessed using a semi-quantitative food frequency questionnaire and dietary phytochemical intake was determined. General linear model was used to compare hs-CRP levels between tertile of DPI. Spearman correlation was used to assess the relationship between hs-CRP and the obesity indexes.
Results: The mean of DPI was 28.54. Significant spearman correlation coefficients were found between hs-CRP and WC (0.43), BMI (0.35), Waist to hip ratio (0.30), visceral adiposity index (0.28) (spearman’s coefficient of correlation). No difference was found for hs-CRP concentration among different tertiles of dietary DPI, after adjustment for confounding factors including BMI, WC, and physical activity (P for trend= 0.964).
Conclusions: The result of the present study showed that hs-CRP is associated with several central obesity indexes but no association was found between hs-CRP and dietary phytochemical index. Further studies using other biomarkers of inflammation and dietary assessment methods are needed to clarify the health effects of flavonoids in humans.
Keywords: Phytochemicals, Inflammation, Women
Full-Text [PDF 477 kb]   (1689 Downloads)    
Article type: Research | Subject: Food Science
Received: 2017/11/22 | Accepted: 2018/07/2 | Published: 2018/09/17
References
1. Mozaffarian D, Benjamin EJ, Go AS, Arnett DK, Blaha MJ, Cushman M, et al. Executive summary: heart disease and stroke Statistics-2016 update: a report from the American Heart Association. Circulation. 2016;133(4):447-54. [DOI:10.1161/CIR.0000000000000366] [PMID]
2. Saadat S, Yousefifard M, Asady H, Jafari AM, Fayaz M, Hosseini M. The most important causes of death in Iranian population; a Retrospective Cohort Study. Emergency. 2015;3(1):16. [PMID] [PMCID]
3. Ridker PM. Clinical application of C-reactive protein for cardiovascular disease detection and prevention. Circulation. 2003;107(3):363-9. [DOI:10.1161/01.CIR.0000053730.47739.3C] [PMID]
4. Salazar J, Martínez MS, Chávez M, Toledo A, A-ez R, Torres Y, et al. C-reactive protein: clinical and epidemiological perspectives. Cardiol Res Pract. 2014;2014, Article ID 605810, 10 pages
5. Esposito K, Giugliano D. Diet and inflammation: a link to metabolic and cardiovascular diseases. Eur Heart J. 2005;27(1):15-20. [DOI:10.1093/eurheartj/ehi605] [PMID]
6. Gencoglu H, Orhan C, Sahin K. Phytochemical Therapies in Vascular Functioning: A Molecular Approach. Curr Vasc Pharmacol. 2017;15(4):327-38. [DOI:10.2174/1570161115666170105122616] [PMID]
7. Rotelli AE, Guardia T, Juárez AO, De la Rocha NE, Pelzer LE. Comparative study of flavonoids in experimental models of inflammation. Pharmacol Res. 2003;48(6):601-6. [DOI:10.1016/S1043-6618(03)00225-1]
8. Jiang Y, Wu S-H, Shu X-O, Xiang Y-B, Ji B-T, Milne GL, et al. Cruciferous vegetable intake is inversely correlated with circulating levels of proinflammatory markers in women. J Acad Nutr Diet. 2014;114(5):700-8. e2.
9. Haghighatdoost F, Bellissimo N, de Zepetnek JOT, Rouhani MH. Association of vegetarian diet with inflammatory biomarkers: a systematic review and meta-analysis of observational studies. Public Health Nutr. 2017;20(15):2713-21. [DOI:10.1017/S1368980017001768] [PMID]
10. Cassidy A, Rogers G, Peterson JJ, Dwyer JT, Lin H, Jacques PF. Higher dietary anthocyanin and flavonol intakes are associated with anti-inflammatory effects in a population of US adults. Am J Clin Nutr. 2015;102(1):172-81. [DOI:10.3945/ajcn.115.108555] [PMID] [PMCID]
11. Jennings A, Welch AA, Spector T, Macgregor A, Cassidy A. Intakes of anthocyanins and flavones are associated with biomarkers of insulin resistance and inflammation in women. J Nutr. 2014;144(2):202-8. [DOI:10.3945/jn.113.184358] [PMID]
12. Alipour B, Rashidkhani B, Edalati S. Dietary flavonoid intake, total antioxidant capacity and lipid oxidative damage: A cross-sectional study of Iranian women. Nutrition. 2016;32(5):566-72. [DOI:10.1016/j.nut.2015.11.011] [PMID]
13. Vitale M, Vaccaro O, Masulli M, Bonora E, Del Prato S, Giorda CB, et al. Polyphenol intake and cardiovascular risk factors in a population with type 2 diabetes: The TOSCA. IT study. Clin Nutr. 2017;36(6):1686-92. [DOI:10.1016/j.clnu.2016.11.002] [PMID]
14. Fardet A. Towards a more Holistic Vision of Human Nutrition to Prevent from Diet-Related Chronic diseases: the reductionist drift. Int J Food Sci Nutr Diet. 2016;5:1-2.
15. Fardet A, Rock E. The search for a new paradigm to study micronutrient and phytochemical bioavailability: from reductionism to holism. Med Hypotheses. 2014;82(2):181-6. [DOI:10.1016/j.mehy.2013.11.035] [PMID]
16. Tapsell LC, Neale EP, Satija A, Hu FB. Foods, nutrients, and dietary patterns: interconnections and implications for dietary guidelines. Advances in Nutrition: . Advances in Nutrition. 2016;7(3):445-54. [DOI:10.3945/an.115.011718] [PMID] [PMCID]
17. Messina M, Lampe JW, Birt DF, Appel LJ. Reductionism and the narrowing nutrition perspective: time for reevaluation and emphasis on food synergy. Int J Food Sci Nutr Diet. 2001;101(12):1416.
18. Fardet A, Rock E. Toward a new philosophy of preventive nutrition: from a reductionist to a holistic paradigm to improve nutritional recommendations. Advances in Nutrition: Adv Nutr. 2014;5(4):430-46. [DOI:10.3945/an.114.006122] [PMID] [PMCID]
19. Jacobs Jr DR, Temple NJ. Food synergy: a paradigm shift in nutrition science. Nutritional health: Springer; 2012. p. 311-22. [PMID]
20. McCarty MF. Proposal for a dietary "phytochemical index". Med Hypotheses. 2004;63(5):813-7. [DOI:10.1016/j.mehy.2002.11.004] [PMID]
21. Bahadoran Z, Golzarand M, Mirmiran P, Saadati N, Azizi F. The association of dietary phytochemical index and cardiometabolic risk factors in adults: Tehran Lipid and Glucose Study. J Hum Nutr Diet. 2013;26(s1):145-53. [DOI:10.1111/jhn.12048] [PMID]
22. Vincent HK, Bourguignon CM, Taylor AG. Relationship of the dietary phytochemical index to weight gain, oxidative stress and inflammation in overweight young adults. J Hum Nutr Diet. 2010;23(1):20-9. [DOI:10.1111/j.1365-277X.2009.00987.x] [PMID] [PMCID]
23. Norman G, Streiner D. Biostatistics: the bare essentials. Hamilton, Ontario: BC Decker. Inc Google Scholar. 2000:106.
24. McKinlay SM, Brambilla DJ, Posner JG. The normal menopause transition. Maturitas. 1992;14(2):103-15. [DOI:10.1016/0378-5122(92)90003-M]
25. Zwirska-Korczala K, Konturek S, Sodowski M, Wylezol M, Kuka D, Sowa P, et al. Basal and Postprandial Plasma Levels of Pyy, Ghrelin. J Physiol Pharmacol. 2007;58:13-35. [PMID]
26. Esfahani FH, Asghari G, Mirmiran P, Azizi F. Reproducibility and relative validity of food group intake in a food frequency questionnaire developed for the Tehran Lipid and Glucose Study. J Epidemiol. 2010;20(2):150-8. [DOI:10.2188/jea.JE20090083] [PMID] [PMCID]
27. Ghaffarpour M H-RA, Kianfar H. The manual for household measures, cooking yields factors and edible portion of foods (In Persian). Tehran: Keshavarzi Press; 1999.
28. Azar M, Sarkisian E. Food composition table of Iran: National Nutrition and Food Research Institute. Shaheed Beheshti University, Tehran. 1980.
29. Aadahl M, Jørgensen T. Validation of a new self-report instrument for measuring physical activity. Med Sci Sports Exerc. 2003;35(7):1196-202. [DOI:10.1249/01.MSS.0000074446.02192.14] [PMID]
30. Ainsworth BE, Haskell WL, Whitt MC, Irwin ML, Swartz AM, Strath SJ, et al. Compendium of physical activities: an update of activity codes and MET intensities. Med Sci Sports Exerc. 2000;32(9; SUPP/1):S498-S504.
31. de Onis M, Onyango AW, Van den Broeck J, Chumlea WC, Martorell R. Measurement and standardization protocols for anthropometry used in the construction of a new international growth reference. Food Nutr Bull. 2004;25(1 Suppl):S27-36. [DOI:10.1177/15648265040251S104] [PMID]
32. Organization WH. Measuring obesity—classification and description of anthropometric data. Report on a WHO consultation of the epidemiology of obesity. Warsaw 21-23 October 1987. Copenhagen: WHO, 1989. Nutrition Unit document, EUR/ICP/NUT. 1987;123.
33. Amato MC, Giordano C. Visceral adiposity index: an indicator of adipose tissue dysfunction. . Int J Endocrinol. 2014;2014.
34. Cassidy A, Minihane A-M. The role of metabolism (and the microbiome) in defining the clinical efficacy of dietary flavonoids. Am J Clin Nutr. 2017;105(1):10-22. [DOI:10.3945/ajcn.116.136051] [PMID] [PMCID]
35. Lampe JW. Interindividual differences in response to plant-based diets: implications for cancer risk. The Am J Clin Nutr. 2009;89(5):1553S-7S. [DOI:10.3945/ajcn.2009.26736D] [PMID] [PMCID]
36. Mossavar-Rahmani Y. Reducing measurement error in nutrition assessment: potential research implications for Iran. . Nutr Food Sci Res. 2017;4(1):3-10. [DOI:10.18869/acadpub.nfsr.4.1.3]
37. Jenab M, Slimani N, Bictash M, Ferrari P, Bingham SA. Biomarkers in nutritional epidemiology: applications, needs and new horizons. Hum Genet. 2009;125(5-6):507-25. [DOI:10.1007/s00439-009-0662-5] [PMID]
38. Kay CD. The future of flavonoid research. Br J Nutr. 2010;104(S3):S91-S5. [DOI:10.1017/S000711451000396X] [PMID]
39. Lotito SB, Zhang W-J, Yang CS, Crozier A, Frei B. Metabolic conversion of dietary flavonoids alters their anti-inflammatory and antioxidant properties. Free Radic Biol Med. 2011;51(2):454-63. [DOI:10.1016/j.freeradbiomed.2011.04.032] [PMID] [PMCID]
40. Williamson G, Clifford MN. Colonic metabolites of berry polyphenols: the missing link to biological activity? Br J Nutr.2010;104(S3):S48-S66. [DOI:10.1017/S0007114510003946] [PMID]
41. Brooks GC, Blaha MJ, Blumenthal RS. Relation of C-reactive protein to abdominal adiposity. Am J Cardiol. 2010;106(1):56-61. [DOI:10.1016/j.amjcard.2010.02.017] [PMID]
42. Al-Daghri NM, Al-Attas OS, Alokail M, Alkharfy K, Wani K, Amer OE, et al. Does visceral adiposity index signify early metabolic risk in children and adolescents?: association with insulin resistance, adipokines, and subclinical inflammation. Pediatr Res. 2013;75(3):459-63. [DOI:10.1038/pr.2013.229] [PMID]
43. Mendez MA. Invited commentary: dietary misreporting as a potential source of bias in diet-disease associations: future directions in nutritional epidemiology research. Am J Epidemiol.2015;181(4):234-6. [DOI:10.1093/aje/kwu306] [PMID]
44. Drewnowski A. New metrics of affordable nutrition: which vegetables provide most nutrients for least cost? J Acad Nutr Diet. 2013;113(9):1182-7. [DOI:10.1016/j.jand.2013.03.015] [PMID]
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Edalati S, Alipour B, Rashidkhani B. Association between Dietary Intake of Phytochemicals and hs-CRP in Healthy Women from Tehran: a Holistic Approach Using Dietary Phytochemical Index . Nutr Food Sci Res 2018; 5 (3) :11-16
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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 5, Issue 3 (Jul-Sep 2018) Back to browse issues page
Nutrition and Food Sciences Research
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